Parustat 40 Tablet is your ally in managing and preventing gout, which turns excess uric acid into painful crystals around your joints. By effectively lowering uric acid levels, Parustat 40 helps reduce inflammation, swelling, and discomfort, allowing you to regain control of your daily life.

This long-term medication is most effective when taken consistently, as your doctor prescribes, even during symptom-free periods. Stopping treatment abruptly can worsen the condition, so stick to the regimen. Pair it with lifestyle changes like staying hydrated, avoiding alcohol, and reducing purine-rich foods (like red meat and seafood) to enhance its benefits.

Common side effects may include mild nausea, joint pain, rashes, or temporary changes in liver function. It’s normal to experience a brief flare-up of gout symptoms when starting the medication, but this subsides as the treatment takes effect. Contact your doctor immediately if you notice signs of liver problems—such as persistent nausea, dark urine, or yellowing of the skin or eyes.

Before beginning Parustat 40, inform your doctor about any heart, thyroid, kidney, or liver conditions. This medication is typically not recommended during pregnancy or breastfeeding unless deemed essential by a healthcare professional. Regular blood tests will ensure your liver is functioning well and the treatment is safe for you.

Take a step toward lasting relief with Parustat 40. With consistent use and proper care, you can break free from gout’s painful grip and focus on living life to the fullest.

1. Prevents Gout Attacks

Parustat 40 Tablet effectively lowers uric acid levels in the blood, preventing the formation of painful crystals in and around the joints. By reducing the likelihood of gout flare-ups, it ensures smoother day-to-day activities and a better quality of life.

2. Reduces Joint Swelling and Pain

By targeting uric acid buildup, Parustat minimises inflammation and swelling in the affected joints. This helps alleviate severe pain, redness, and warmth, promoting faster recovery and improved mobility.

3. Long-Term Protection Against Gout

Designed for consistent, long-term use, Parustat not only treats current symptoms but also prevents future attacks. Regular use lowers uric acid levels, providing a sustainable solution to chronic gout issues.

4. Supports Kidney Health

High uric acid levels can lead to kidney stones and other complications. Parustat helps reduce uric acid accumulation in the kidneys, protecting against potential damage and promoting overall kidney health.

5. Improves Quality of Life

By effectively managing gout symptoms and preventing recurrent attacks, Parustat allows individuals to maintain an active lifestyle, free from the debilitating pain and discomfort associated with gout.

With Parustat 40, you manage gout effectively and take proactive steps to protect your joints, kidneys, and overall health for the future.

Most side effects of Parustat 40 Tablet are mild and tend to subside as your body adjusts to the medication. However, if they persist or cause concern, consult your doctor for advice.

Common side effects include:

• Nausea

• Skin rash or irritation

• Abnormal liver function

• Joint pain
  
  

If any of these side effects interfere with your daily activities or worsen over time, your doctor can provide effective strategies to manage them. Always follow medical guidance to ensure safe use.

• Follow Your Doctor’s Advice: Take Parustat 40mg Tablet exactly as prescribed by your doctor. Adhere to the recommended dose and duration for optimal results.

• Swallow Whole: Swallow the tablet with a glass of water. Do not chew, crush, or break the tablet, as it may affect its effectiveness.

• Take With Food: Always take Parustat 40mg Tablet with food to prevent stomach upset and enhance absorption.

• Stick to a Schedule: For consistent relief, try to take the medicine at the same time each day.

Consult your doctor if you have any questions or concerns about how to use this medication.

Parustat 40 Tablet contains Febuxostat (40mg), which helps manage gout by reducing uric acid levels in the body. Here's how it works:

1. Inhibition of Xanthine Oxidase:

Febuxostat selectively inhibits xanthine oxidase, an enzyme responsible for converting purines into uric acid. 

2. Reduction of Uric Acid Production:

By blocking xanthine oxidase, Febuxostat decreases the production of uric acid, leading to lower levels in the bloodstream.

3. Prevention of Crystal Formation:

Lower uric acid levels reduce the likelihood of urate crystal formation in joints, which is the primary cause of gout pain and inflammation.

4. Alleviation of Gout Symptoms:

With fewer crystals forming, symptoms such as joint pain, swelling, and redness are alleviated, improving overall joint function.

5. Long-Term Management:

• Alcohol: Exercise caution while consuming alcohol with Parustat 40 Tablet. Alcohol may increase the risk of side effects. Always consult your doctor for personalized advice.

• Pregnancy: Parustat 40 Tablet may not be safe during pregnancy. Although limited human studies are available, animal studies indicate potential risks to the developing baby. Your doctor will assess the benefits and risks before prescribing this medication.

• Breastfeeding: This medication is likely unsafe for use while breastfeeding. Limited studies suggest it may pass into breast milk and potentially harm the baby. Discuss alternatives with your doctor.

• Driving: Parustat 40 Tablet may cause dizziness, blurred vision, or tingling sensations. Avoid driving or operating heavy machinery until you know how this medication affects you.

• Kidney Health: Use Parustat 40 Tablet with caution if you have severe kidney disease. Your doctor may adjust the dosage based on your condition and recommend regular monitoring.

• Liver Health: Patients with severe liver disease should use Parustat 40 Tablet cautiously. Dose adjustments may be required, and close monitoring by your doctor is essential.

Always inform your healthcare provider about any pre-existing medical conditions or medications you are currently taking to ensure safe and effective use of Parustat 40 Tablet.

Missed a Dose

If you forget to take a dose of Parustat 40 Tablet, take it as soon as you remember. However, if your next dose is approaching, skip the missed dose and continue with your regular schedule. Avoid taking a double dose to make up for the missed one.

Overdose
In case of an overdose, seek immediate medical attention. Taking more than the recommended dose may increase the risk of side effects. Always follow your doctor’s prescribed dosage to ensure safe and effective use of Parustat 40 Tablet.

1. Consistent Medication Use: Take Parustat 40 Tablet as prescribed, at the same time each day, with or without food, to maintain steady uric acid levels.

2. Hydration: Drink at least 2-3 liters of water daily to help flush excess uric acid from your body. 

3. Dietary Choices: Limit intake of purine-rich foods such as red meat, organ meats, and certain seafood to reduce uric acid production. 

4. Alcohol Consumption: Avoid alcohol, especially beer and spirits, as they can trigger gout flare-ups. 

5. Monitor for Side Effects: Be alert for any unusual symptoms like rashes, itching, breathing difficulties, fever, or swelling, and inform your doctor immediately if they occur.

6. Maintain a Healthy Weight: Achieving and maintaining a healthy weight can decrease the frequency of gout attacks. 

7. Regular Physical Activity: Engage in moderate exercise to improve joint function and overall health, but avoid activities that put excessive strain on affected joints. 

8. Limit Sugary Beverages: Reduce consumption of sugary drinks, as they can increase uric acid levels. 

9. Rest During Flare-Ups: During acute gout attacks, rest and elevate the affected joint to reduce swelling and pain. 

10. Regular Medical Check-ups: Schedule periodic visits with your healthcare provider to monitor uric acid levels and assess the effectiveness of your treatment plan.

When taking Parustat 40 Tablet (Febuxostat), it’s important to be cautious about its interactions with other medicines. Combining certain drugs with Parustat can alter their effects, increase side effects, or lead to undesirable reactions. 
Below are some key interactions:

1. Rosuvastatin (For Cholesterol)

Effect: Parustat may increase blood levels of Rosuvastatin.

Risk: Can cause unexplained muscle pain, tenderness, or weakness.

Action: Avoid combining these medications. If necessary, your doctor may monitor and adjust the dose of Rosuvastatin.

2. Aminophylline (For Breathing Disorders)

Forms: Both oral and injection routes.

Effect: Parustat may increase Aminophylline levels in the blood.

Risk: Symptoms like nausea, palpitations, or headaches.

Action: If both medicines are required, your doctor will monitor your condition and adjust the Aminophylline dose as needed.

3. Azathioprine (For Autoimmune Conditions)

Effect: Parustat may elevate blood levels of Azathioprine.

Risk: May cause abdominal pain, blurred vision, flushing, or discomfort.

Action: It is generally advised to avoid using these drugs together. If absolutely necessary, doses will be carefully monitored and adjusted by your doctor.

4. Mercaptopurine (For Cancer and Immune Disorders)

Effect: Parustat may raise Mercaptopurine levels in the blood.

Risk: Potential symptoms include abdominal pain, blurred vision, flushing, or discomfort.

Action: Avoid using these medications simultaneously. If required, your doctor will closely monitor and adjust doses accordingly.

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